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What Is Rett’s Autism? Understanding Rett Syndrome and Its Connection to Autism

Rebecca Hollister

PhD, BCBA-D

Seventeen years in ABA has shaped Rebecca's philosophy: good therapy isn't just about data — it's about dignity.

Families exploring autism may hear the term Rett’s autism,” but what does it mean? Rett syndrome is a rare genetic neurological disorder that primarily affects girls and causes severe challenges with speech, movement, and coordination. In the past, it was sometimes referred to as “Rett’s autism” because children with Rett syndrome often show autism-like behaviors, especially in early development.


Today, experts recognize Rett syndrome and autism as two distinct conditions. While both may involve communication difficulties, repetitive behaviors, and sensory sensitivities, Rett syndrome is caused by specific genetic mutations (most commonly in the MECP2 gene). Unlike autism, which varies widely across the spectrum, Rett syndrome usually follows a predictable progression, including loss of motor skills after a period of normal early development.


Understanding the difference is important for families seeking support and treatment. Autism is lifelong and managed with behavioral and therapeutic interventions, while Rett syndrome requires medical management in addition to supportive therapies.


At Steady Strides ABA, we are committed to helping families navigate these complex conditions. Whether supporting children with autism or addressing overlapping challenges, our goal is to provide compassionate, individualized care that helps every child thrive.


Frequently Asked Questions

  • Is Rett syndrome the same as autism?

    No. Rett syndrome is a genetic disorder, though it can share features with autism.

  • Why was Rett syndrome once called “Rett’s autism”?

    Because early symptoms resemble autism, though it is now classified separately.

  • Can ABA therapy help children with Rett syndrome?

    While medical care is essential, ABA strategies can support communication, daily living, and behavioral needs.

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